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GHK-Cu

Copper tripeptide · Dermatology

4.84 reviews
Analyzed in the USA
GHK-Cu 50 mg — MX-1 Labs
CAS#
89030-95-5
Formula
C14H22CuN6O4
M.W.
401.91 g/mol
Sequence
GHK
PURITY99% HPLC
RUONot for human or veterinary use
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MX$518.00

Ships in 24–72 business hours from CDMX · Free shipping over MX$2,500.00

GHK-Cu 50 mg (copper glycyl-L-histidyl-L-lysine) is an endogenous tripeptide naturally present in human plasma, supplied as a sterile lyophilized powder with the characteristic blue crystalline appearance of the copper-peptide complex. ≥99% purity verified by HPLC, batch CoA.

Certificate of Analysis
Lot
s3hzq3t
Expires
2028-02
Chromatographic purity
≥99.9%
Mass Spectral Match
Confirmed
Content
45 mg · 90% of label
Analyzed by
Krause Analytical · 2026-02
Preview COA
Certificate of Analysis preview
View full COA
Technical specifications
Molecular weight
340.38 Da (Cu complex)
Sequence
Gly-His-Lys · Cu²⁺
Format
Sterile lyophilized
Content
50 mg per vial
Purity
≥99% verified by HPLC in batch CoA
Appearance
Characteristic blue crystalline powder
Identity
Confirmed by MS and atomic absorption of Cu
Endotoxins (LAL)
< 5 EU/mg
Water content (Karl Fischer)
< 6%
Amino acid analysis
Composition confirmed by acid hydrolysis

About GHK-Cu 50 mg

GHK-Cu (copper glycyl-L-histidyl-L-lysine) is an endogenous tripeptide naturally present in human plasma, originally described by Dr. Loren Pickart in 1973 [1]. The classic literature on the compound reports that plasma GHK levels decline significantly with biological age.

The systematic review by Pickart and Margolina published in Oxidative Medicine and Cellular Longevity (2018) consolidates the accumulated preclinical evidence on its regenerative properties in skin, connective tissues, and wound-healing models [2]. Transcriptomic studies by Pickart and colleagues (2015) suggest that GHK-Cu modulates the expression of several thousand genes involved in the cutaneous regenerative response and tissue remodeling [3].

MX-1 Labs distributes GHK-Cu 50 mg in Mexico as a scientific research compound in sterile lyophilized format, with the characteristic blue crystalline powder of the copper-peptide complex and complete per-batch analytical documentation. The product is intended exclusively for in vitro laboratory research; it is not a medication, supplement, or cosmetic consumer product.

Research applications

In preclinical in vitro models, the complex stimulates type I and III collagen synthesis in dermal fibroblasts, inhibits the expression of matrix metalloproteinases (MMPs) associated with tissue damage, and modulates the cellular antioxidant response. The copper ion (Cu²⁺) coordinated to the tripeptide contributes enzymatic cofactor activity for superoxide dismutase (SOD), one of the primary endogenous antioxidant systems [2][3]. The copper:peptide stoichiometric ratio is verified analytically to ensure the integrity of the bioactive complex in every batch.

Storage and handling

Sealed vial of GHK-Cu 50 mg: protect from direct light, humidity, and prolonged air exposure to preserve the integrity of the copper-peptide complex, which is chemically sensitive to oxidation. Once the experimental solution is prepared, keep refrigerated under documented conditions with strict records of opening date, diluent used, and workstation conditions. As a sensitive copper-peptide complex, repeated freeze-thaw cycles of the prepared solution are not recommended; apply the institutional criteria defined in the lab's SOP. Discard the material at any change in color from the original blue crystalline appearance, turbidity, or the appearance of particles.

Scientific references

  1. Pickart L. The human tri-peptide GHK and tissue remodeling. J Biomater Sci Polym Ed 2008; 19(8):969–988. View source on PubMed →
  2. Pickart L, Margolina A. Regenerative and Protective Actions of the GHK-Cu Peptide. Oxid Med Cell Longev 2018; Article ID 7591840. View source on PubMed →
  3. Pickart L, Vasquez-Soltero JM, Margolina A. GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration. BioMed Res Int 2015. View source on PubMed →

Frequently asked questions

Is it legal to buy research peptides in Mexico?

Yes. Research peptides are sold legally in Mexico strictly for laboratory research use — not for human or veterinary consumption, diagnosis, or treatment. MX-1 Labs sells for research purposes only; at checkout you confirm compliant use under applicable law (COFEPRIS) and your lab's protocols. Nationwide shipping from CDMX.

Reviews

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